Pulmonary artery sarcoma: An important mimic of pulmonary embolism—Case reports and literature review

Respirology Case Reports

Anas Naeem¹  Suhrid Lodh²  Ajantha Raguparan³  Colin Tuft³  Steven Lindstrom³  Krishan Maheepala³ 

[1] Intensive Care Unit St George Hospital Sydney New South Wales Australia;Radiology Department St George Hospital Sydney New South Wales Australia;Respiratory and Sleep Medicine Department St George Hospital Sydney New South Wales Australia;

关键词: intimal sarcoma;    lung embolism;    lung sarcoma;    pulmonary artery;    pulmonary embolism;   

DOI  :  10.1002/rcr2.897

来源: DOAJ

【 摘 要 】

Abstract Pulmonary artery intimal sarcoma (PAIS) is a rare malignancy which closely mimics acute or chronic pulmonary thromboembolism. There are clinical and radiological characteristics which may raise suspicion of this important differential diagnosis. These include disproportionately low d‐dimer, troponin T or NT‐proBNP, as well as characteristic findings on CT pulmonary angiography such as the ‘wall eclipsing sign’ and an non‐dependent position of filling defects in the large arteries. Prompt diagnosis avoids inappropriate anticoagulation and facilitates early surgical management which may improve prognosis. There is emerging evidence of an effective treatment paradigm with surgical resection and adjuvant chemotherapy. We present two cases of PAIS diagnosed at a single centre within a 2‐year period. We review the literature and demonstrate the features at presentation in our cases which were suggestive of the diagnosis.

【 授权许可】

Unknown