Facile sonochemical-assisted synthesis of orthorhombic phase black phosphorus/rGO hybrids for effective photothermal therapy

Nanophotonics

Liu Quan¹  Liu Liping¹  Wang Hanyue¹  Du Zhiyong¹  Bao Shiyun¹  Wang Dou¹  Ge Chenchen¹  Qi Xiang²  Ren Xiaohui²  Li Zhongjun³  Qiu Meng³  Zhang Han³  Xu Yijun³  Liang Weiyuan³ 

[1] Department of Hepatobiliary and Pancreatic Surgery, The 2nd Clinical Medicine College (Shenzhen People’s Hospital) of Jinan University, Shenzhen 518020, P.R. China;Hunan Key Laboratory of Micro-Nano Energy Materials and Devices, Laboratory for Quantum Engineering and Micro-Nano Energy Technology and School of Physics and Optoelectronic, Xiangtan University, Hunan 411105, P.R. China;Shenzhen Engineering Laboratory of Phosphorene and Optoelectronics, Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, International Collaborative Laboratory of 2D Materials for Optoelectronics Science and Technology of Ministry of Education, Institute of Microscale Optoelectronics, Guangdong Laboratory of Artificial Intelligence and Digital Economy (SZ), College of Physics and Optoelectronic Engineering, Shenzhen University, Shenzhen 518060, P.R. China;

关键词: cancer;    sonochemical;    black phosphorus;    orthorhombic phase;    hybrid;    photothermal therapy;   

DOI  :  10.1515/nanoph-2019-0476

来源: DOAJ

【 摘 要 】

Two-dimensional black phosphorus (BP) has been demonstrated to be promising in photoelectronic devices, electrode materials, and biomedicine owing to its outstanding properties. However, the application of BP has been hindered by harsh preparation conditions, high costs, and easy degradation in ambient condition. Herein, we report a facile and cost-effective strategy for synthesis of orthorhombic phase BP and a kind of BP-reduced graphene oxide (BP/rGO) hybrids in which BP remains stable for more than 4 weeks ascribed to the formation of phosphorus-carbon covalent bonds between BP and rGO as well as the protection effect of the unique wrinkle morphology of rGO nanosheets. Surface modification BP/rGO hybrids (PEGylated BP/rGO) exhibit excellent photothermal performance with photothermal conversion efficiency as high as 57.79% at 808 nm. The BP/rGO hybrids exhibit enhanced antitumor effects both in vitro and in vivo, showing promising perspectives in biomedicine.

【 授权许可】

Unknown