Results from the intracarotid amytal procedure in patients with uni or bitemporal lobe epilepsy and mesial sclerosis Resultados do teste intracarotídeo de amital em pacientes com epilepsia uni ou bilateral do lobo temporal e esclerose mesial

Arquivos de Neuro-Psiquiatria

关键词: amital;    epilepsia;    lobo temporal;    cirurgia;    amytal;    epilepsy;    temporal lobe;    surgery;   

DOI  :  10.1590/S0004-282X1995000400011

来源: DOAJ

【 摘 要 】

This study discusses the results from the IAP and its lateralizing and prognostic value in patients with temporal lobe epilepsy (TLE) and mesial temporal sclerosis (MTS). Eighteen patients were submitted to the IAP. Fifteen had bitemporal and 3 unitemporal lobe epilepsies. All patients had MTS on MRI and in one there was an unrelated lesion in the contralateral hippocampus. Nine bitemporal patients passed after the injection ipsilateral to the MTS and 4 failed bilaterally. One bitemporal passed bilaterally. Seven of these bitemporal patients passed an injection ipsilateral to MTS and failed on contralateral injection. Two of the unitemporal lobe patients passed the ipsilateral injection and failed the contralateral one. One of the unitemporal lobe patients failed bilaterally the IAP. Overall, 56% of the group disclosed the pass ipsi/fail contralateral pattern in the IAP. Eight patients were operated, are seizure free and had no additional memory deficit. Many patients with TLE were found to have the pass ipsi-/fail contralateral pattern in the IAP. This might prove to be of lateralizing and prognostic value in such cases.
Este estudo discute os resultados obtidos no teste de amital s��dico (TAS) intracarotídeo e seu valor prognóstico e de lateralização em pacientes com epilepsia do lobo temporal (ELT) e esclerose mesial temporal (EMT). Dezoito pacientes foram submetidos ao TAS. Quinze possuíam epilepsias bitemporais e 3 unitemporais. Todos os pacientes possuíam EMT na RMN e em 1 existia uma calcificação hipocampal contralateral. Nove pacientes bitemporais passaram a injeção ipsilateral à EMT e 4 falharam bilateralmente. Um paciente bitemporal passou bilateralmente. Sete pacientes bitemporais passaram a injeção ipsilateral à EMT e falharam do outro lado. Dois pacientes unitemporais tiveram este mesmo comportamento. Um paciente unitemporal falhou bilateralmente no TAS. Globalmente, 56% dos pacientes apresentaram o padrão passa ipsi- / falha contralateral no TAS. Oito pacientes foram operados, estão sem crises e não tiveram déficits adicionais de memória. Muitos pacientes com ELT possuem o padrão passa ipsi- / falha contralateral no TAS. Isto deve representar fator de lateralização e prognóstico relevante.

【 授权许可】

Unknown