Human iPSC banking: barriers and opportunities

Journal of Biomedical Science

Chun-Lin Liu¹  Ching-Ying Huang¹  Yu-Che Cheng¹  Chien-Yu Ting¹  Patrick C. H. Hsieh¹  Martin W. Nicholson¹  Yueh-Ting Chiu¹ 

[1] Institute of Biomedical Sciences, Academia Sinica;

关键词: Induced pluripotent stem cell (iPSC);    Cell bank;    Personalized medicine;   

DOI  :  10.1186/s12929-019-0578-x

来源: DOAJ

【 摘 要 】

Abstract The introduction of induced pluripotent stem cells (iPSCs) has opened up the potential for personalized cell therapies and ushered in new opportunities for regenerative medicine, disease modeling, iPSC-based drug discovery and toxicity assessment. Over the past 10 years, several initiatives have been established that aim to collect and generate a large amount of human iPSCs for scientific research purposes. In this review, we compare the construction and operation strategy of some iPSC banks as well as their ongoing development. We also introduce the technical challenges and offer future perspectives pertaining to the establishment and management of iPSC banks.

【 授权许可】

Unknown