Brain activation and inhibition after acupuncture at Taichong and Taixi: resting-state functional magnetic resonance imaging

Neural Regeneration Research

关键词: Alzheimer′s disease;    amyloid-β;    astrocytes;    Ca 2+;    calcilytic;    calcium-sensing receptor;    nitromemantine;    NPS 2143;    α7-nicotinic acetylcholine receptor;    nerve regeneration;    spinal cord injury;    surgical decompression;    tumor necrosis factor α;    cell apoptosis;    neurological function;    neural regeneration;    nerve regeneration;    spinal cord injury;    contusion;    Nogo-A;    axon growth;    immunohistochemistry;    fluorescent quantitative PCR;    neural regeneration;    nerve regeneration;    spinal cord injury;    Schwann cells;    cell transplantation;    edaravone;    motor function;    electrophysiological function;    neural regeneration;    nerve regeneration;    electroacupuncture;    intervertebral disc;    blood circulation;    inflammation;    neuroprotection;    motor function;    neurons;    NSFC grants;    neural regeneration;    nerve regeneration;    astrocytoma;    mice;    immunodeficiency (BALB/c) mice;    Notch;    nestin;    glial fibrillary acidic protein;    CD133;    spinal cord;    brain;    MRI;    neural regeneration;    nerve regeneration;    earthquake;    peripheral nerve injury;    LSUHSC score;    compartment syndrome;    surgery therapy;    physiotherapy;    nerve decompression;    neural regeneration;    nerve regeneration;    brachial plexus injury;    human amniotic epithelial cells;    forepaw function;    stress relaxation;    creep;    viscoelasticity;    neural regeneration;    nerve regeneration;    peripheral nerve injury;    injection injury;    cyclosporine A;    penicillin G potassium;    Wallerian degeneration;    neuroelectrophysiology;    neural regeneration;    nerve regeneration;    Oenanthe javanica extract;    cell proliferation;    neuroblast differentiation;    brain-derived neurotrophic factor;    vascular endothelial growth factor;    rat;    neural regeneration;    nerve regeneration;    middle cerebral artery occlusion;    brain injury;    neurons;    astrocytes;    oligodendrocytes;    neural progenitor cells;    proliferation;    differentiation;    neurogenesis;    neural regeneration;    nerve regeneration;    cerebral ischemia;    point application;    Angong Niuhuang sticker;    brain injury;    neurological functions;    acupuncture;    traditional Chinese medicine;    NSFC grants;    neural regeneration;    nerve regeneration;    acupuncture;    neuroimaging;    resting-state functional magnetic resonance imaging;    Taichong (LR3);    Taixi (KI3);    amplitude of low-frequency fluctuation;    Brodmann area 11;    Brodmann area 18;    Brodmann area 19;    Brodmann area 44;    posterior lobe of the cerebellum;    neural regeneration;   

DOI  :  10.4103/1673-5374.152385

来源: DOAJ

【 摘 要 】

Acupuncture can induce changes in the brain. However, the majority of studies to date have focused on a single acupoint at a time. In the present study, we observed activity changes in the brains of healthy volunteers before and after acupuncture at Taichong (LR3) and Taixi (KI3) using resting-state functional magnetic resonance imaging. Fifteen healthy volunteers underwent resting-state functional magnetic resonance imaging of the brain 15 minutes before acupuncture, then received acupuncture at Taichong and Taixi using the nail-pressing needle insertion method, after which the needle was retained in place for 30 minutes. Fifteen minutes after withdrawal of the needle, the volunteers underwent a further session of resting-state functional magnetic resonance imaging, which revealed that the amplitude of low-frequency fluctuation, a measure of spontaneous neuronal activity, increased mainly in the cerebral occipital lobe and middle occipital gyrus (Brodmann area 18/19), inferior occipital gyrus (Brodmann area 18) and cuneus (Brodmann area 18), but decreased mainly in the gyrus rectus of the frontal lobe (Brodmann area 11), inferior frontal gyrus (Brodmann area 44) and the center of the posterior lobe of the cerebellum. The present findings indicate that acupuncture at Taichong and Taixi specifically promote blood flow and activation in the brain areas related to vision, emotion and cognition, and inhibit brain areas related to emotion, attention, phonological and semantic processing, and memory.

【 授权许可】

Unknown