Flow Cytometry in the Diagnosis of Canine T-Cell Lymphoma

Frontiers in Veterinary Science

Stefano Comazzi¹  Fulvio Riondato² 

[1] Dipartimento di Medicina Veterinaria, Università degli Studi di Milano, Lodi, Italy;Dipartimento di Scienze Veterinarie, Università degli Studi di Torino, Grugliasco, Italy;

关键词: dog;    lymphoma;    T-cell;    flow cytometry;    diagnosis;    prognosis;   

DOI  :  10.3389/fvets.2021.600963

来源: DOAJ

【 摘 要 】

T cell lymphoma (TCL) is a heterogenous group of lymphoid malignancies representing about 30–40% of all canine lymphomas and often harboring a very aggressive behavior. WHO classification identifies the majority of TCLs as peripheral TCL, but other subtypes with peculiar presentation and outcome have been recognized. This review aims to explore the use of flow cytometry for refining the diagnosis of canine TCL, putting a particular emphasis on the identification of some peculiar immunotypes, such as T zone lymphoma; on the investigation of putative prognostic markers; and on the evaluation of lymphoma stage and of the minimal residual disease.

【 授权许可】

Unknown