Astragalus polysaccharides protects thapsigargin-induced endoplasmic reticulum stress in HT29 cells

Open Life Sciences

Dai Yan-Cheng¹  Zhang Ya-Li¹  Tang Zhi-Peng¹  Zheng Lie¹  Chen De-Liang¹  Chen Xuan² 

[1] Institute of Digestive Diseases, LongHua Hospital, Shanghai University of Traditional Chinese Medicine, 725 Wanping Road, Shanghai200032, China;Shanghai University of Traditional Chinese Medicine, Shanghai201203, China;

关键词: astragalus polysaccharides;    thapsigargin;    er stress;    ht29 cells;    perk-eif2a signaling;   

DOI  :  10.1515/biol-2019-0055

来源: DOAJ

【 摘 要 】

This study investigates the effect of astragalus polysaccharides (APS) in protecting against thapsigargin-induced endoplasmic reticulum (ER) stress in HT29 cells by suppressing the PERK-eIF2a signaling pathway.

【 授权许可】

Unknown