Chemical Constituents of Murraya tetramera Huang and Their Repellent Activity against Tribolium castaneum

Molecules

Zhu-Feng Geng¹  Zhi-Wei Deng¹  Jun-Yu Liang²  Chun-Xue You²  Wen-Juan Zhang²  Shan-Shan Guo²  Shu-Shan Du²  Ning Lei³ 

[1] Analytical and Testing Center, Beijing Normal University, Beijing 100875, China;Beijing Key Laboratory of Traditional Chinese Medicine Protection and Utilization, Faculty of Geographical Science, Beijing Normal University, No.19, Xinjiekouwai Street, Beijing 100875, China;Department of Pharmacy, The General Hospital of the PLA Rocket Force, Xicheng District, Beijing 100088, China;

关键词: T. castaneum;    M. tetramera;    repellent activity;    grey relational analysis;    chemical constituents;   

DOI  :  10.3390/molecules22081379

来源: DOAJ

【 摘 要 】

Sixteen compounds were isolated from the leaves and stems of Murraya tetramera Huang. Based on the NMR and MS spectral results, the structures were determined. It was confirmed that the isolated compounds included three new compounds (9, 10 and 13) and one new natural product (8), which were identified asmurratetra A (9), murratetra B (10), murratetra C (13) and [2-(7-methoxy-2-oxochromen-8-yl)-3-methylbut-2-enyl]3-methylbut-2-enoate (8), respectively. Meanwhile, the repellent activity against Tribolium castaneum was investigated for 13 of these isolated compounds. The results showed that the tested compounds had various levels of repellent activity against T. castaneum. Among them, compounds 1 (4(15)-eudesmene-1β,6α-diol), 11 (isoferulic acid) and 16 (2,3-dihydroxypropyl hexadecanoate) showed fair repellent activity against T. castaneum. They might be considered as potential leading compounds for the development of natural repellents.

【 授权许可】

Unknown