Brain monitoring using near-infrared spectroscopy to predict outcome after cardiac arrest: a novel phenotype in a rat model of cardiac arrest

Journal of Intensive Care

Lance B. Becker¹  Rishabh Choudhary¹  Daniel M. Rolston¹  Kei Hayashida¹  Ryosuke Takegawa¹ 

[1] Laboratory for Critical Care Physiology, Feinstein Institutes for Medical Research, Northwell Health System;

关键词: Cardiac arrest;    Cardiopulmonary resuscitation;    Near-infrared spectroscopy;    NIRS;    Cerebral oxygen saturation;    rSO2;   

DOI  :  10.1186/s40560-020-00521-9

来源: DOAJ

【 摘 要 】

Abstract Improving neurological outcomes after cardiac arrest (CA) is the most important patient-oriented outcome for CA research. Near-infrared spectroscopy (NIRS) enables a non-invasive, real-time measurement of regional cerebral oxygen saturation. Here, we demonstrate a novel, non-invasive measurement using NIRS, termed modified cerebral oximetry index (mCOx), to distinguish the severity of brain injury after CA. We aimed to test the feasibility of this method to predict neurological outcome after asphyxial CA in rats. Our results suggest that mCOx is feasible shortly after resuscitation and can provide a surrogate measure for the severity of brain injury in a rat asphyxia CA model.

【 授权许可】

Unknown