Effects of PM2.5 on Chronic Airway Diseases: A Review of Research Progress

Atmosphere

Xiaoju Liu¹  Xin Li¹ 

[1] Department of Gerontal Respiratory Medicine, The First Hospital of Lanzhou University, Lanzhou 730000, China;

关键词: fine particulate matter (PM_2.5);    chronic airway disease;    health effects;    inflammatory responses;    oxidative stress;    alveolar macrophages;   

DOI  :  10.3390/atmos12081068

来源: DOAJ

【 摘 要 】

The adverse effects of polluted air on human health have been increasingly appreciated worldwide. It is estimated that outdoor air pollution is associated with the death of 4.2 million people globally each year. Accumulating epidemiological studies indicate that exposure to ambient fine particulate matter (PM_2.5), one of the important air pollutants, significantly contributes to respiratory mortality and morbidity. PM_2.5 causes lung damage mainly by inducing inflammatory response and oxidative stress. In this paper, we reviewed the research results of our group on the effects of PM_2.5 on chronic obstructive pulmonary disease, asthma, and lung cancer. And recent research progress on epidemiological studies and potential mechanisms were also discussed. Reducing air pollution, although remaining a major challenge, is the best and most effective way to prevent the onset and progression of respiratory diseases.

【 授权许可】

Unknown