Atypical Frontotemporal Connectivity of Cognitive Empathy in Male Adolescents With Conduct Disorder

Frontiers in Psychology

卷:9

Yidian Gao¹  Xiang Wang¹  Daifeng Dong¹  Shuqiao Yao¹  Yali Jiang¹  Qingsen Ming² 

[1] China National Clinical Research Center on Mental Disorders (Xiangya), Changsha, China;

[2] Department of Psychiatry, The First Affiliated Hospital of Soochow University, Suzhou, China;

[3] Medical Psychological Center, The Second Xiangya Hospital of Central South University, Changsha, China;

[4] Medical Psychological Institute of Central South University, Changsha, China;

关键词: conduct disorder;    cognitive empathy;    affective empathy;    functional connectivity;    adolescent;   

DOI  :  10.3389/fpsyg.2018.02778

来源: DOAJ

【 摘 要 】

Background: It has been suggested that adolescents with conduct disorder (CD) may have a deficit in the affective and cognitive domains empathy, but studies exploring networks within the key brain regions of affective and cognitive empathy in adolescents with CD are lacking.Methods: Functional connectivity (FC) analyses among key brain regions of the affective and cognitive empathy with resting-state functional magnetic resonance imaging (fMRI) were conducted in 30 adolescent boys with CD and 33 demographically matched healthy controls (HCs).Results: Atypical FC within the key brain regions of affective empathy was not observed in CD adolescents. However, we found that CD adolescents showed decreased frontotemporal connectivity within the key brain regions of cognitive empathy in relation to HCs, that is, the FCs between right temporoparietal junction and ventromedial prefrontal cortex as well as dorsomedial prefrontal cortex.Conclusion: These findings may provide insight into neural mechanism underlying a cognitive empathy deficiency of CD adolescents from the perspective of FC.

【 授权许可】

Unknown