Cold case: The disappearance of Egypt bee virus, a fourth distinct master strain of deformed wing virus linked to honeybee mortality in 1970’s Egypt

Virology Journal

卷:19

Anne Dalmon¹  Fanny Mondet¹  Hussein Migdadi²  Nizar J. Haddad²  Eugene V. Ryabov³  Anna K. Childers³  Emily J. Remnant⁴  Owen N. Wright⁵  Vincent Doublet⁶  Robyn Manley⁶  Lena Wilfert⁶  John M. K. Roberts⁷  Fredrik Granberg⁸  Joachim R. de Miranda⁹  Rene Kaden⁹  Meghan O. Milbrath⁹  Jelle Matthijnssens¹⁰  Ward Deboutte¹⁰  Sebastian Gisder¹¹  Laura E. Brettell¹²  Elke Genersch¹³  Nor Chejanovsky¹⁴  Noa Sela¹⁴  Ivan Meeus¹⁵  Guy Smagghe¹⁵  Haftom Gebremedhn¹⁶  Dirk C. de Graaf¹⁶  Brenda V. Ball¹⁷  Hema Somanathan¹⁸  Stephen J. Martin¹⁹ 

[1] Abeilles et Environnement, INRAE;

[2] Bee Research Department, National Agricultural Research Center;

[3] Bee Research Laboratory, Beltsville Agricultural Research Center, USDA;

[4] Behaviour, Ecology and Evolution (BEE) Lab, School of Life and Environmental Sciences, The University of Sydney;

[5] Centre for Research in Animal Behaviour, College of Life and Environmental Sciences, University of Exeter;

[6] College of Life and Environmental Sciences, University of Exeter;

[7] Commonwealth Scientific and Industrial Research Organisation;

[8] Department of Biomedical Sciences and Veterinary Public Health, Swedish University of Agricultural Sciences;

[9] Department of Ecology, Swedish University of Agricultural Sciences;

[10] Department of Microbiology, Immunology and Transplantation, Rega Institute, Laboratory for Clinical and Epidemiological Virology, University of Leuven;

[11] Department of Molecular Microbiology and Bee Diseases, Institute for Bee Research;

[12] Hawkesbury Institute for the Environment, Western Sydney University;

[13] Institut Für Mikrobiologie Und Tierseuchen, Fachbereich Veterinärmedizin, Freie Universität Berlin;

[14] Institute of Plant Protection;

[15] Laboratory of Agrozoology, Department of Plants and Crops, Ghent University;

[16] Laboratory of Molecular Entomology and Bee Pathology, Ghent University;

[17] Rothamsted Research;

[18] School of Biology, Indian Institute of Science Education and Research;

[19] School of Environment and Life Sciences, University of Salford;

关键词: Egypt bee virus;    Deformed wing virus;    Master strain;    Varroa destructor;    Honeybee;    Apis mellifera;   

DOI  :  10.1186/s12985-022-01740-2

来源: DOAJ

【 摘 要 】

Abstract In 1977, a sample of diseased adult honeybees (Apis mellifera) from Egypt was found to contain large amounts of a previously unknown virus, Egypt bee virus, which was subsequently shown to be serologically related to deformed wing virus (DWV). By sequencing the original isolate, we demonstrate that Egypt bee virus is in fact a fourth unique, major variant of DWV (DWV-D): more closely related to DWV-C than to either DWV-A or DWV-B. DWV-A and DWV-B are the most common DWV variants worldwide due to their close relationship and transmission by Varroa destructor. However, we could not find any trace of DWV-D in several hundred RNA sequencing libraries from a worldwide selection of honeybee, varroa and bumblebee samples. This means that DWV-D has either become extinct, been replaced by other DWV variants better adapted to varroa-mediated transmission, or persists only in a narrow geographic or host range, isolated from common bee and beekeeping trade routes.

【 授权许可】

Unknown