Clinical Value of Cell Block in the Diagnosis of Malignant Pleural Effusion

Chinese Journal of Lung Cancer

卷:20

Diansheng ZHONG¹  Lisha ZHANG¹  Yi SHAO¹  Fanlu MENG¹  Fangyuan CHENG¹  Tao YU¹  Xintong WANG¹ 

[1] Department of Medical Oncology, Tianjin Medical University General Hospital, Tianjin 300052, China;

关键词: Malignant pleural effusion;    Natural sedimentation;    Plasma coagulation method;    Imunohistochemical staining;    Clinical value;   

DOI  :  10.3779/j.issn.1009-3419.2017.06.05

来源: DOAJ

【 摘 要 】

Background and objective Malignant pleural effusion (MPE) is due tumor which arises from the mesothelium or metastases from tumor origniating other sites. Generally, the prognosis of MPE is poor, in the premise of reducing the pain of patients, as soon as possible make clear the property of pleural effusion and cause of the disesease, rightly and quickly, providing effective information for subsequent treatment. Methods The cell block of 103 patients by using natural sedimentation or plasma coagulation method combined with HE staining and immunohistochemical staining method maked clear diagnosis and compared with other methods. Results 90 patients were diagnosed by cell block section from 103 patients who had MPE (diagnostic rate 87.4%); 32 cases were diagnosed by cell block section only, 74 cases pointed out that the pathological type , 23 cases even pointed out the primary lesions; 71 cases examined other invasive methods at the same time, the diagnostic rate was 87.3% and 81.7%; the detection rate of cell block section and cytological smear in detecting malignant tumor cells was 86.7%and 44.0% respectively. Conclusion Cell block can not only increase the diagnosis, in contrast to cytological smear, and own the same diagnostic rate compared with other invasive methods, but also can confirm pathological type and primary lesion; especially, for other invasive methods, cell block method is a preferable complementary method, and that cell block method maybe the only way for some patients.

【 授权许可】

Unknown