FENO AND ATOPY IN PEDIATRIC ASTHMA

Romanian Journal of Pediatrics

卷:64

Elena Petrisor¹  Alina Oprea¹  Cristiana Stanciulescu²  Daniela Pacurar²  Carmen Zapucioiu²  Dumitru Oraseanu²  Mirela Chiru² 

[1] “Carol Davila” University of Medicine and Pharmacy, Bucharest;

[2] “Grigore Alexandrescu” Emergency Clinical Hospital for Children, Bucharest;

关键词: feno;    eosinophilia;    ige;    asthma;    atopy;   

DOI  :  10.37897/RJP.2015.2.6

来源: DOAJ

【 摘 要 】

Objectives. The aim of this study was to determine the manner in which the level of exhaled nitric oxide (FENO)infl uences the atopic status in children with asthma.Methods. The study included 92 asthmatic children (aged 5-18 years) admitted on the Pediatric Clinic of “Grigore Alexandrescu” Emergency Clinical Hospital for Children. The atopic status was evaluated through anamnesis, clinical examination and laboratory determination of serum eosinophils and total Ig E. All children underwent measurement of FENO.Results. Children with atopic asthma had higher levels of FENO than children with nonatopic asthma. TheFENO values correlate with eosinophilia and high values of immunoglobulin E.Conclusion. FENO is a useful marker for the evaluation of airway infl ammation in children with atopic asthma.

【 授权许可】

Unknown