Sex hormone allergy: clinical aspects, causes and therapeutic strategies – Update and secondary publication

World Allergy Organization Journal

卷:10

A. N. Jensen¹  K. Walch²  E. Untersmayr³ 

[1] AllergyCare – Allergy Diagnosis and Study Center Vienna;

[2] Department of Gynecological Endocrinology and Reproductive Medicine, Clinic of Obstetrics and Gynecology, Medical University of Vienna;

[3] Institute for Pathophysiology and Allergy Research, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna;

关键词: Allergy;    Sex hormone;    Progesterone;    Estrogen;    Female;    Sex;   

DOI  :  10.1186/s40413-017-0176-x

来源: DOAJ

【 摘 要 】

Abstract Sex hormone allergy as a clinical syndrome has been known for almost a century. Due to the diversity of clinical presentation regarding symptoms and disease patterns, the optimal patient care represents an enormous interdisciplinary challenge. Frequently, hypersensitivity reactions affect more than one sex hormone and double positive tests for estrogen and progesterone have been described. Since the menstrual cycle dependent symptoms range from skin afflictions, gynecological problems to non-specific reactions, different pathophysiological mechanisms seem likely. Various desensitization protocols are described as causal treatment options, but are rarely applied in clinical routine. Consequently, major research efforts with a quick translation of therapeutic interventions into clinical practice will be crucial to help affected patients in the future.

【 授权许可】

Unknown