Association between Prenatal Exposure to Household Pesticides and Neonatal Weight and Length Growth in the Japan Environment and Children’s Study

International Journal of Environmental Research and Public Health

卷:17

Mayumi Sugiura-Ogasawara¹  Takahiro Kurihara²  Hirohisa Kano²  Yuki Ito²  Hirotaka Sato²  Takeshi Ebara²  Michihiro Kamijima²  Hazuki Tamada²  Taro Matsuki²  Sayaka Kato²  Shinji Saitoh³  Yasuyuki Yamada⁴ 

[1] Department of Obstetrics and Gynecology, Graduate School of Medical Sciences, Nagoya City University, Mizuho-ku, Nagoya, Aichi 4678601, Japan;

[2] Department of Occupational and Environmental Health, Graduate School of Medical Sciences, Nagoya City University, Mizuho-ku, Nagoya, Aichi 4678601, Japan;

[3] Department of Pediatrics and Neonatology, Graduate School of Medical Sciences, Nagoya City University, Mizuho-ku, Nagoya, Aichi 4678601, Japan;

[4] Graduate School of Health and Sports Science, Juntendo University, Inzai, Chiba 2701695, Japan;

关键词: pesticides;    pregnancy;    children;    birth weight;    birth length;    JECS;   

DOI  :  10.3390/ijerph17124608

来源: DOAJ

【 摘 要 】

The effects of prenatal exposure to household pesticides on fetal and neonatal growth have not been fully clarified. The present study aims to determine the effects of prenatal exposure to pesticides on neonates’ body size and growth during the first month. This study included 93,718 pairs of pregnant women and their children from the Japan Environment and Children’s Study. Participants completed self-reporting questionnaires during their second or third trimesters on their demographic characteristics and frequency of pesticide use during pregnancy. Child weight, length, and sex were obtained from medical record transcripts. Birth weight and length, as well as weight and length changes over the first month, were estimated using an analysis of covariance. Frequency of exposure to almost all pesticides had no effects on birth weight and length. However, we found small but significant associations (i) between the use of fumigation insecticides and decreased birth weight, and (ii) between frequencies of exposure to pyrethroid pesticides, especially mosquito coils/mats, and suppression of neonatal length growth. Prenatal exposure to household pesticides, especially those containing pyrethroids, might adversely influence fetal and postnatal growth trajectories.

【 授权许可】

Unknown