Magnesium Promotes the Regeneration of the Peripheral Nerve

Frontiers in Cell and Developmental Biology

卷:9

Shiwen Zhang¹  Weimin Lin¹  Binjing Zhang¹  Jinglan Zhang²  Jingxin Zhang² 

[1] National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China;

[2] State Key Laboratory of Oral Diseases &

关键词: peripheral nerve repair;    nerve regeneration;    magnesium;    biodegradability;    biocompatibility;   

DOI  :  10.3389/fcell.2021.717854

来源: DOAJ

【 摘 要 】

Peripheral nerve injury is a common complication in trauma, and regeneration and function recovery are clinical challenges. It is indispensable to find a suitable material to promote peripheral nerve regeneration due to the limited capacity of peripheral nerve regeneration, which is not an easy task to design a material with good biocompatibility, appropriate degradability. Magnesium has captured increasing attention during the past years as suitable materials. However, there are little types of research on magnesium promoting peripheral nerve regeneration. In this review, we conclude the possible mechanism of magnesium ion promoting peripheral nerve regeneration and the properties and application of different kinds of magnesium-based biomaterials, such as magnesium filaments, magnesium alloys, and others, in which we found some shortcomings and challenges. So, magnesium can promote peripheral nerve regeneration with both challenge and potential.

【 授权许可】

Unknown