Vitamin D nutritional status in the adult population in Colombia – An analytical cross-sectional study

Heliyon

卷:6

Mera-Mamián Andry¹  Agredo Valentina²  Pinzón-Fernández María Virginia³  Vargas-Uricoechea Hernando⁴ 

[1] Corresponding author.;

[2] Department of Internal Medicine, Universidad del Cauca, Popayán-Cauca, Colombia;

[3] Epidemiology and Statistics Research Group, Universidad CES, Medellín, Colombia;

[4] Metabolic Diseases Study Group, Department of Internal Medicine, Universidad del Cauca, Popayán-Cauca, Colombia;

关键词: Biological sciences;    Chemistry;    Environmental science;    Food science;    Health sciences;    Vitamin D;   

DOI  :  

来源: DOAJ

【 摘 要 】

Background: The key role of Vitamin D is to maintain an adequate calcium and phosphorus metabolism. Vitamin D plays an antagonistic role with the parathyroid hormone. 25 OH Vitamin D is the major circulating form and the best indicator to monitor Vitamin D levels. Methods: A cross-sectional study was conducted in 1339 individuals ≥18 years old. The main objective was to establish the nutritional status of Vitamin D and its association with PTH and ionized calcium levels. Other objectives were to compare the levels of 25 OH Vitamin D based on sun exposure habits, and to identify the minimum cut-off point for the levels of 25 OH Vitamin D that could give rise to a concomitant increase in PTH and ionized calcium levels. Results: 14.2% of participants presented Vitamin D deficiency, and 28.8% presented insufficiency; ≥89% of the participants with deficiency or insufficiency were exposed to sunlight <30 minutes per week. A value of 25 OH Vitamin D >30 ng/mL was associated with a more stable and “flat” PTH value. The median of 25 OH Vit-D associated with hypercalcemia was <10 ng/mL. Conclusion: In Colombia, low 25 OH Vitamin D values are highly prevalent; this may be accounted for by poor sun-exposure habits and frequent use of sunscreen. Just as in other similar trials, the lower the levels of 25 OH Vit-D, the higher the effect on PTH and ionized calcium elevation.

【 授权许可】

Unknown