Immunopathology of RSV: An Updated Review

Viruses

卷:13

Harrison C. Bergeron¹  Ralph A. Tripp¹ 

[1] Department of Infectious Diseases, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA;

关键词: respiratory syncytial virus;    RSV;    immunity;    immunopathology;    host–pathogen interaction;   

DOI  :  10.3390/v13122478

来源: DOAJ

【 摘 要 】

RSV is a leading cause of respiratory tract disease in infants and the elderly. RSV has limited therapeutic interventions and no FDA-approved vaccine. Gaps in our understanding of virus–host interactions and immunity contribute to the lack of biological countermeasures. This review updates the current understanding of RSV immunity and immunopathology with a focus on interferon responses, animal modeling, and correlates of protection.

【 授权许可】

Unknown