Conceptually New Entries into Cells

CHIMIA

卷:65

Charlotte Gehin¹  Andrea Fin¹  Naomi Sakai¹  Eun-Kyoung Bang¹  David Alonso Doval¹  Stefan Matile²  Howard Riezman³ 

[1] ;

[2] School of Chemistry and Biochemistry, University of Geneva, CH-1211 Geneva, Switzerland. [e-mail];

[3] School of Chemistry and Biochemistry, University of Geneva, CH-1211 Geneva, Switzerland;

关键词: Cell-penetrating peptides;    Cellular uptake;    Sensing;    Sirna;    Transport;   

DOI  :  10.2533/chimia.2011.853

来源: DOAJ

【 摘 要 】

This article summarizes the background and a few preliminary results concerning project 7 of the NCCR Chemical Biology. The general objective is to explore new concepts for cellular uptake, membrane tunneling, sensing and labeling. Emphasis is on the use of dynamic covalent chemistry for counterion activation, slow release of polyions and fluorescent probes, and the generation of activator libraries and polyions that grow and shrink.

【 授权许可】

Unknown