The Habitual Diet of Dutch Adult Patients with Eosinophilic Esophagitis has Pro-Inflammatory Properties and Low Diet Quality Scores

Nutrients

卷:13

Mylene van Doorn¹  LucienF. Harthoorn¹  SimoneR. B. M. Eussen¹  BramD. van Rhijn²  AlbertJ. Bredenoord³  MarijnJ. Warners⁴  MarlouL. A. de Kroon⁵  BerberJ. Vlieg-Boerstra⁶  BridgetA. Holmes⁷ 

[1] Danone Nutricia Research, 3508 TC Utrecht, The Netherlands;

[2] Department of Dermatology & Allergology, University Medical Center, 3584 CX Utrecht, The Netherlands;

[3] Department of Gastroenterology & Hepatology, Academic Medical Center, 1105 AZ Amsterdam, The Netherlands;

[4] Department of Gastroenterology & Hepatology, Sint Antonius Hospital, 3435 CM Nieuwegein, The Netherlands;

[5] Department of Health Sciences, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands;

[6] Department of Pediatrics, OLVG Hospital, 1091 AC Amsterdam, The Netherlands;

[7] Global Nutrition Department, Danone Nutricia Research, 91120 Palaiseau, France;

关键词: diet;    diet quality;    food intakes;    adults;    eosinophilic esophagitis;   

DOI  :  10.3390/nu13010214

来源: DOAJ

【 摘 要 】

We determined the nutritional adequacy and overall quality of the diets of adult patients with eosinophilic esophagitis (EoE). Dietary intakes stratified by sex and age were compared to Dietary Reference Values (DRV). Overall diet quality was assessed by two independent Diet-Quality-Indices scores, the PANDiet and DHD-index, and compared to age- and gender-matched subjects from the general population. Lastly, food and nutrient intakes of EoE patients were compared to intakes of the general population. Saturated fat intake was significantly higher and dietary fiber intake significantly lower than the DRV in both males and females. In males, the DRV were not reached for potassium, magnesium, selenium, and vitamins A and D. In females, the DRV were not reached for iron, sodium, potassium, selenium, and vitamins A, B2, C and D. EoE patients had a significantly lower PANDiet and DHD-index compared to the general population, although the relative intake (per 1000 kcal) of vegetables/fruits/olives was significantly higher (yet still up to 65% below the recommended daily amounts) and alcohol intake was significantly lower compared to the general Dutch population. In conclusion, the composition of the habitual diet of adult EoE patients has several pro-inflammatory and thus unfavorable immunomodulatory properties, just as the general Dutch population, and EoE patients had lower overall diet quality scores than the general population. Due to the observational character of this study, further research is needed to explore whether this contributes to the development and progression of EoE.

【 授权许可】

Unknown