High-Intensity Interval Training Improves Cardiac Autonomic Function in Patients with Type 2 Diabetes: A Randomized Controlled Trial

Biology

卷:11

Jordana Campos Martins de Oliveira¹  Lucas Raphael Bento Silva¹  Maria Sebastiana Silva²  Thomas Beltrame³  Paulo Gentil⁴  Vitor Alves Marques⁴  Ana Cristina Silva Rebelo⁴  Camila Simões Seguro⁵ 

[1] Department of Physical Education, Araguaia University Center, Goiania 74223-060, Brazil;

[2] Faculty of Physical Education and Dance, Federal University of Goiás, Goiania 74690-900, Brazil;

[3] Institute of Computing, University of Campinas, Campinas 13083-852, Brazil;

[4] Post-Graduate Program in Health Sciences, Faculty of Medicine, Federal University of Goias, Goiania 74605-050, Brazil;

[5] Post-Graduate Program in Nutrition and Health, Faculty of Nutrition, Federal University of Goias, Goiania 74605-080, Brazil;

关键词: type 2 diabetes;    physical exercise;    high-intensity interval training;    cardiac autonomic modulation;    heart rate recovery;    heart rate variability;   

DOI  :  10.3390/biology11010066

来源: DOAJ

【 摘 要 】

Different exercise models have been used in patients with type 2 diabetes mellitus (T2D), like moderate intensity continuous training (MICT) and high intensity interval training (HIIT); however, their effects on autonomic modulation are unknown. The present study aimed to compare the effects of different exercise modes on autonomic modulation in patients with T2D. In total, 44 adults with >5 years of T2D diagnosis were recruited and stratified into three groups: HIIT-30:30 (n = 15, age 59.13 ± 5.57 years) that performed 20 repetitions of 30 s at 100% of VO2peak with passive recovery, HIIT-2:2 (n = 14, age 61.20 ± 2.88) that performed 5 repetitions of 2 min at 100% of VO2peak with passive recovery, and MICT (n = 15, age 58.50 ± 5.26) that performed 14 min of continuous exercise at 70% of VO2peak. All participants underwent anamnesis and evaluation of cardiorespiratory fitness and cardiac autonomic modulation. All protocols were equated by total distance and were performed two times per week for 8 weeks. Group × time interactions were observed for resting heart rate (HRrest) [F(2.82) = 3.641; p = 0.031] and SDNN [F(2.82) = 3.462; p = 0.036]. Only the HIIT-30:30 group significantly reduced SDNN (p = 0.002 and 0.025, respectively). HRrest reduced more in the HIIT-30:30 group compared with the MICT group (p = 0.038). Group × time interactions were also observed for offTAU [F(2.82) = 3.146; p = 0.048] and offTMR [F(2.82) = 4.424; p = 0.015]. The MICT group presented increased values of offTAU compared with the HIIT-30:30 and HIIT-2:2 groups (p = 0.001 and 0.013, respectively), representing a slower HR response after eight weeks of intervention. HIIT, specially HIIT-30:30, represents a promising measure for improving autonomic modulation in patients with T2D.

【 授权许可】

Unknown