Polar Compounds Isolated from the Leaves of Albertisia delagoensis (Menispermaceae)

Molecules

卷:16

关键词: Albertisia delagoensis;    traditional medicine;    roemrefidine;    allantoic acid;    HPLC-NMR;   

DOI  :  10.3390/molecules16119153

来源: DOAJ

【 摘 要 】

Aqueous infusions of the leaves of the shrub Albertisia delagoensis (Menispermaceae) are used in South Africa in traditional Zulu medicine to alleviate a variety of symptoms, including fever, and intestinal problems. We report the analysis of such an aqueous extract using the HPLC-NMR technique. A number of polar compounds were identified, including proto-quercitol, nicotinic acid, allantoic acid, 3,4-dihydroxy-benzoic acid, phthalic acid and the aporphine alkaloid derivative roemrefidine. Allantoic acid and roemrefidine have been fully characterised by 1H- and 13C-NMR and mass spectrometry. Earlier reports of antiplasmodial activity of roemrefidine and of A. delagoensis extracts are correlated with this study and with the antipyretic properties of neutral aqueous extracts.

【 授权许可】

Unknown