Candidiasis and opportunistic mycosis in human

Novel Research in Microbiology Journal

卷:3

Feto Haji¹  Addisu Assefa¹  Habtamu Tedila¹ 

[1] College of Natural and Computational Science, Department of Biology (Stream of Applied Microbiology), Madda Walabu University, PO box 247, Bale Robe, Ethiopia;

关键词: candida albicans;    cryptococcus gattii;    aspergillus spp.;    fusarium spp.;    ;    pneumocytis spp;    human diseases;   

DOI  :  10.21608/NRMJ.2019.28105

来源: DOAJ

【 摘 要 】

Pathogenic fungi cause serious diseases in humans, plants and animals. These include mainly, Candida spp.,Aspergillus spp., Cryptococcus spp., Fusarium spp., and Pneumocytis spp. Candida species cause infections inindividuals with deficient immune systems, and Th1-type cell-mediated immunity (CMI) is required for clearanceof this fungal infection. Candida albicans is an opportunistic pathogen of humans and has a parasexual cycle thatappears to be stimulated by environmental stresses. Aspergilli represent the most common pathogenic speciesespecially for Aspergillus flavus and A. fumigatus. A. flavus produces aflatoxins which act both as toxins andcarcinogens, and can potentially contaminate foods. A. clavatus causes allergic disease of human; its symptomsinclude; fever, cough chest pain or breathlessness. Cryptococcus neoformans is one of the most effective humanpathogens; it causes severe form of meningitis and meningo-encephalitis in patients with HIV infection andAIDS. C. gattii was endemic to tropical parts of Africa and Australia; cause disease in immunocompromisedpeople. Fusarium spp. are important pathogenic mold fungi; second only to Aspergillus spp. Fusaria also producetoxins that could cause poisoning through consumption of toxin-contaminated foods. The aims of this reviewwere to highlight the etiology, risk factors, pathogenesis, human defence and preventive measures of some of themost common fungal human pathogens, to avoid infections and their subsequent cause of fatal diseases.

【 授权许可】

Unknown