In vitro oxidative stress regulatory potential of Citrullus colocynthis and Tephrosia apollinea

Acta Pharmaceutica

卷:68

Hussain Javid¹  Mabood Fazal¹  Adnan Muhammad²  Khan Abdul Latif³  Ali Liaqat³  Al-Mawali Narjis³  Rizvi Tania Shamim³  Al-Harrasi Ahmed³ 

[1] Department of Biological Science and Chemistry, University of Nizwa, Birkat Al-Mouz, Nizwa-616, Oman;

[2] Department of Botany, Kohat University of Science and Technology, Kohat-26000, Pakistan;

[3] UoN Chair of Oman’s Medicinal Plants and Marine Natural Products, University of Nizwa, Birkat Al-Mouz, Nizwa-616, Oman;

关键词: citrullus colocynthis;    tephrosia apollinea;    oxidative stress;    total phenolics;   

DOI  :  10.2478/acph-2018-0012

来源: DOAJ

【 摘 要 】

The present study investigates the potential role of medicinal plants Citrullus colocynthis and Tephrosia apollinea in ameliorating the oxidative stress developed during the generation of reactive oxygen species. Organic extracts of different organs (leaf, stem and root) of these medicinal plants obtained in n-hexane, chloroform, n-butanol and water were assayed for radical scavenging, total antioxidant capacity, anti-lipid peroxidation and reduced glutathione. The total phenolic content (TPC) of both selected medicinal plants was also evaluated. The results indicated that extracts of T. apollinea leaf, stem and root have higher TPC compared to those of C. colocynthis. Similarly, the results of the present study revealed higher bioactivity of C. colocynthis than that of T. apollinea in various antioxidant assays. Various plant parts of each plant were also compared.

【 授权许可】

Unknown