NMR-Based Metabolomic Analysis of Spatial Variationin Soft Corals

Marine Drugs

卷:12

Zhiwei Deng¹  Zhufeng Geng¹  Huijuan Liu²  Dawei Chen³  Yinping Li⁴  Jiao Han⁴  Ruiqi Sun⁴  Qing He⁴  Shushan Du⁵  Wenhan Lin⁶ 

[1] Analytic and Testing Center, Beijing Normal University, Beijing 100875, China;

[2] Beijing Forensic Science Institute, Beijing 100875, China;

[3] China National Center for Food Safety Risk Assessment, Beijing 100022, China;

[4] College of Chemistry, Beijing Normal University, Beijing 100875, China;

[5] State Key Laboratory of Earth Surface Processes and Resource Ecology, Beijing Normal University, Beijing 100875, China;

[6] State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100083, China;

关键词: soft coral;    NMR spectroscopy;    chemometrics;    spatial variation;   

DOI  :  10.3390/md12041876

来源: DOAJ

【 摘 要 】

Soft corals are common marine organisms that inhabit tropical and subtropical oceans. They are shown to be rich source of secondary metabolites with biological activities. In this work, soft corals from two geographical locations were investigated using 1H-NMR spectroscopy coupled with multivariate statistical analysis at the metabolic level. A partial least-squares discriminant analysis showed clear separation among extracts of soft corals grown in Sanya Bay and Weizhou Island. The specific markers that contributed to discrimination between soft corals in two origins belonged to terpenes, sterols andN-containing compounds. The satisfied precision of classification obtained indicates this approach using combined 1H-NMR and chemometrics is effective to discriminate soft corals collected in different geographical locations. The results revealed that metabolites of soft corals evidently depended on living environmental condition, which would provide valuable information for further relevant coastal marine environment evaluation.

【 授权许可】

Unknown