Effect of carvacrol on pulmonary function tests, and total and differential white blood cell counts in healthy volunteers: A randomized clinical trial

Avicenna Journal of Phytomedicine

卷:9

Marzieh Boskabady¹  Mohammad Hossein Boskabady²  Vahideh Ghorani³ 

[1] Dental Materials Research Center, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran;

[2] Department of Physiology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

[3] Neurogenic Inflammation Research Center, Mashhad University of Medical Sciences, Mashhad, Iran;

[4] Pharmaciutical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran Department of Physiology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran;

关键词: Carvacrol;    Pulmonary function tests;    White blood cells;    Healthy volunteers;   

DOI  :  10.22038/ajp.2018.11679

来源: DOAJ

【 摘 要 】

Objective: This is the first study to evaluate the effect of carvacrol on pulmonary function tests (PFT), and total and differential white blood cell (WBC) counts in healthy volunteers.Materials and Methods: Thirty healthy volunteers were recruited based on the inclusion and exclusion criteria. The subjects were treated with two doses of carvacrol (1 and 2 mg/kg/day) for 1 month. Total and differential WBC counts and PFT were examined before and after the treatment period.Results: There were no statistically significant differences in terms of total and differential WBC counts between pre and post-treatment with the two doses of carvacrol. Also, results of PFT tests indicated that administration of 1 mg/kg/day carvacrol had no effect on PFT parameters when comparing post-treatment values with pre-treatment values. Treatment with 2 mg/kg/day carvacrol for 1 month increased forced expiratory volume in first second (FEV1) (p

【 授权许可】

Unknown