Non-Coding RNAs as Regulators of Myogenesis and Postexercise Muscle Regeneration

International Journal of Molecular Sciences

卷:22

Anita Florkowska¹  Maria A. Ciemerych¹  Karolina Archacka¹  Karolina Romanczuk¹ 

[1] Department of Cytology, Institute of Developmental Biology and Biomedical Sciences, Faculty of Biology, University of Warsaw, Miecznikowa 1, 02-096 Warsaw, Poland;

关键词: mammals;    human;    mouse;    miRNA;    lncRNA;    myogenesis;   

DOI  :  10.3390/ijms222111568

来源: DOAJ

【 摘 要 】

miRNAs and lncRNAs do not encode proteins, but they play an important role in the regulation of gene expression. They differ in length, biogenesis, and mode of action. In this work, we focus on the selected miRNAs and lncRNAs involved in the regulation of myogenesis and muscle regeneration. We present selected miRNAs and lncRNAs that have been shown to control myogenic differentiation and show that manipulation of their levels could be used to improve myogenic differentiation of various types of stem and progenitor cells. Finally, we discuss how physical activity affects miRNA and lncRNA expression and how it affects muscle well-being.

【 授权许可】

Unknown