Thuringiensin: A Thermostable Secondary Metabolite from Bacillus thuringiensis with Insecticidal Activity against aWide Range of Insects

Toxins

卷:6

Xiaoyan Liu¹  Lin Li²  Ming Sun²  Ziniu Yu²  Lifang Ruan²  Donghai Peng² 

[1] Hubei Biopesticide Engineering Research Center, Hubei Academy of Agricultural Sciences,Wuhan 430064, China;

[2] State Key Laboratory of Agricultural Microbiology, College of Life Science and Technology, Huazhong Agricultural University, Wuhan 430070, China;

关键词: thuringiensin;    Bacillus thuringiensis;    insecticidal mechanism;    genetic determinants;   

DOI  :  10.3390/toxins6082229

来源: DOAJ

【 摘 要 】

Thuringiensin (Thu), also known as β-exotoxin, is a thermostable secondary metabolite secreted by Bacillus thuringiensis. It has insecticidal activity against a wide range of insects, including species belonging to the orders Diptera, Coleoptera, Lepidoptera, Hymenoptera, Orthoptera, and Isoptera, and several nematode species. The chemical formula of Thu is C22H32O19N5P, and it is composed of adenosine, glucose, phosphoric acid, and gluconic diacid. In contrast to the more frequently studied insecticidal crystal protein, Thu is not a protein but a small molecule oligosaccharide. In this review, a detailed and updated description of the characteristics, structure, insecticidal mechanism, separation and purification technology, and genetic determinants of Thu is provided.

【 授权许可】

Unknown