Crystal structure of (1′S,2′S,3S)-1′-benzoyl-2′-(4-methoxyphenyl)-1-methyl-2′,5′,6′,10b′-tetrahydro-1′H-spiro[indoline-3,3′-pyrrolo[2,1-a]isoquinolin]-2-one

Acta Crystallographica Section E: Crystallographic Communications

卷:76

Birkumar Singh Huidrom¹  Yuvaraj Panneerselvam¹  Jyoti Boruah Dhruba²  Kannan Piskala Subburaman³  Stella Mary⁴  Janet Priyavathani Selvaraj⁴ 

[1] Academy of Scientific and Innovative Research (AcSIR), CSIR-NEIST Campus, India;

[2] Applied Organic Chemistry Group, Chemical Science and Technology Division, CSIR-North East Institute of Science and Technology, Jorhat-785006, India;

[3] Department of Physics, Kings Engineering College, Irungattukottai, Sriperumbudur, Chennai–602117, Tamilnadu, India;

[4] Department of Physics, St.Peter's University, Avadi, Chennai-600054, Tamilnadu, India;

关键词: crystal structure;    spiro;    indoline;    tetrahydroisoquinoline;    pyrrolidine;   

DOI  :  10.1107/S2056989020010300

来源: DOAJ

【 摘 要 】

In the title spiro compound, C34H30N2O3, the central pyrrolidine ring is fused with the tetrahydroisoquinoline ring, both having distorted envelope conformations, with the flap atoms being C and N, respectively. The methoxyphenyl group is attached to the pyrrolidine ring, and is disordered over two positions, with refined occupancies of 0.638 (6):0.362 (6) Å. The central pyrrolidine ring is inclined relative to the tetrahydroisoquinoline group, such that the dihedral between the non-flap atoms of each ring system is 11.29 (7)°. The spiro-linkage creates a dihedral angle of 83.26 (5)° between the indolinone ring and the non-flap atoms of the pyrrolidine ring. In the crystal, molecules are linked via C—H...O hydrogen bonds. For the major disorder component, these form C(11) chains that propagate parallel to the a axis.

【 授权许可】

Unknown