Human Genomics | 卷:4 |
Intronic polymorphisms of cytochromes P450 | |
关键词: pharmacogenetics; splicing defects; drug response; drug metabolism; POR; | |
DOI : 10.1186/1479-7364-4-6-402 | |
来源: DOAJ |
【 摘 要 】
Abstract
The cytochrome P450 enzymes active in drug metabolism are highly polymorphic. Most allelic variants have been described for enzymes encoded by the cytochrome P450 family 2 (CYP2) gene family, which has 252 different alleles. The intronic polymorphisms in the cytochrome P450 genes account for only a small number of the important variant alleles; however, the most important ones are
【 授权许可】
Unknown