Long-Term Outcomes of Homografts in the Aortic Valve and Root Position: A 20-Year Experience

Korean Journal of Thoracic and Cardiovascular Surgery

卷:49

Joo Yeon Kim¹  Sung-Ho Jung¹  Jae Won Lee¹  Joon Bum Kim¹  Cheol Hyun Chung¹  Suk Jung Choo¹ 

[1] Asan Medical Center;

关键词: Aortic root;    Aortic valve;    Homograft;    Allograft;   

DOI  :  10.5090/kjtcs.2016.49.4.258

来源: DOAJ

【 摘 要 】

Background: The advantages of using a homograft in valve replacement surgery are the excellent hemodynamicprofile, low risk of thromboembolism, and low risk of prosthetic valve infection. The aim of this studywas to evaluate the long-term outcomes of homograft implantation in the aortic valve position. Methods: Thisis a retrospective study of 33 patients (＞20 years old) who underwent aortic valve replacement or root replacementwith homografts between April 1995 and May 2015. Valves were collected within 24 hours fromexplanted hearts of heart transplant recipients (＜60 years) and organ donors who were not suitable forheart transplantation. The median follow-up duration was 35.6 months (range, 0 to 168 months). Results:Aortic homografts were used in all patients. The 30-day mortality rate was 9.1%. The 1- and 5-year survivalrates were 80.0%±7.3% and 60.8%±10.1%, respectively. The 1-, 5-, and 10-year freedom from reoperationrates were 92.3%±5.2%, 68.9%±10.2%, and 50.3%±13.6%, respectively. The 1-, 5-, and 10-year freedom fromsignificant aortic dysfunction rates were 91.7%±8.0%, 41.7%±14.2%, and 25.0%±12.5%, respectively.Conclusion: Homografts had the advantages of a good hemodynamic profile and low risk of thromboembolicevents, and with good outcomes in cases of aortitis.

【 授权许可】

Unknown