Interpretation on pediatric⁃type diffuse gliomas in the 2021 WHO Classification of Tumors of the Central Nervous System (fifth edition)

Chinese Journal of Contemporary Neurology and Neurosurgery

卷:21

WEI Bo⁃xing¹  ZHANG Jian⁃min²  SUN Chong⁃ran²  XU Su⁃su³  XU Jing⁃hong⁴  ZHANG Bu⁃yi⁴  JIANG Biao⁵  DONG Fei⁵ 

[1] Department of Neurosurgery,The Second Affiliated Hospital of Zhejiang University School of Medicine;

[2] Department of Neurosurgery, The Second Affiliated Hospital of Zhejiang University School of Medicine;

[3] Department of Pathology,The Second Affiliated Hospital of Zhejiang University School of Medicine;

[4] Department of Pathology, The Second Affiliated Hospital of Zhejiang University School of Medicine;

[5] Department of Radiology, The Second Affiliated Hospital of Zhejiang University School of Medicine;

关键词: glioma;    central nervous system neoplasms;    guidelines;    world health organization;    magnetic resonance imaging;    pathology;    child;    review;   

DOI  :  10.3969/j.issn.1672⁃6731.2021.09.009

来源: DOAJ

【 摘 要 】

The 2021 WHO Classification of Tumors of the Central Nervous System (fifth edition) was released. One of the biggest differences between new edition tumors classification and the previous editions is that the pediatric ⁃ type diffuse low ⁃ grade gliomas and the pediatric ⁃ type diffuse high ⁃ grade gliomas are classified into independent tumor families. This change is based on the fact that although pediatric ⁃ type diffuse gliomas morphologically resemble their adult counterparts, while their molecular genetics features are completely different, and the prognosis of these tumors with different molecular genetics features is different accordingly, so different treatment strategies are needed. Physicians and surgeons need to know of the features of these pediatric ⁃ type diffuse gliomas. This paper reviews the existing literature, and the pathological reports and imaging data of our hospital, summarizes the imaging and pathological diagnostic features, as well as the clinical manifestations, prognostic features and treatment suggestions of these pediatric⁃type diffuse gliomas. This review will provide an annotation from the view of diagnosis and treatment on pediatric⁃type diffuse gliomas for the physicians and surgeons.

【 授权许可】

Unknown