Molecular Profile of Skin Cancer

Applied Sciences

卷:11

Ramona Gabriela Ursu¹  Vlad Porumb²  Cosmin Gabriel Popa³  Mihaela Monica Scutariu⁴  Elena Porumb-Andrese⁵  Thomas Gabriel Schreiner⁶  Ionut Luchian⁷  Ioana Mârţu⁸  Darius Sandu⁸ 

[1] Departament of Microbiology, University of Medicine and Pharmacy ‘Grigore T. Popa’, 700115 Iaşi, Romania;

[2] Departament of Surgery, University of Medicine and Pharmacy ‘Grigore T. Popa’, 700115 Iaşi, Romania;

[3] Department of Anatomy and Embriology, University of Medicine and Pharmacy ‘Grigore T. Popa’, 700115 Iaşi, Romania;

[4] Department of Dental Technology, Faculty of Dental Medicine, University of Medicine and Pharmacy ‘Grigore T. Popa’, 700115 Iaşi, Romania;

[5] Department of Dermatology, University of Medicine and Pharmacy ‘Grigore T. Popa’, 700115 Iaşi, Romania;

[6] Department of Neurology, University of Medicine and Pharmacy ‘Grigore T. Popa’, 700115 Iaşi, Romania;

[7] Department of Periodontology, University of Medicine and Pharmacy ‘Grigore T. Popa’, 700115 Iaşi, Romania;

[8] Faculty of Dental Medicine, University of Medicine and Pharmacy ‘Grigore T. Popa’, 700115 Iaşi, Romania;

关键词: gene mutations;    basal cell carcinoma;    squamous cell carcinoma;    melanoma;   

DOI  :  10.3390/app11199142

来源: DOAJ

【 摘 要 】

Neoplasia occurs as a result of genetic mutations. Research evaluating the association between gene mutations and skin cancer is limited and has produced inconsistent results. There are no established guidelines for screening skin cancer at molecular level. It should also be noted that the combinations of some mutations may play a role in skin tumors’ biology and immune response. There are three major types of skin cancer, and the originality of this study comes from its approach of each of them.

【 授权许可】

Unknown