Novel edifice calix[4]pyrrole derivatives as a potential sensor for the detection of analytes and in silico computational behaviour

Talanta Open

卷:5

Krunal M. Modi¹  Ajay L. Desai²  Keyur D. Bhatt²  Chirag Patel³  Shibu G. Pillai⁴ 

[1] Corresponding author.;

[2] Department of Chemistry, Faculty of Science, Ganpat University, Kherva, Mehsana, Gujarat 384012, India;

[3] Department of Humanities and Science, School of Engineering, Indrashil University, Mehsana, Gujarat 382740, India;

[4] National Cancer Institute (NCI) National Institutes of Health, 9000 Rockville Pike, Bethesda, MD, United States;

关键词: Calix[4]pyrrole;    Sensor;    Antibiotics;    Metal ions;    Computational studies;    Fluorescence;   

DOI  :  

来源: DOAJ

【 摘 要 】

The beguiling properties of functionalised calix[4]pyrrole has garnered a lot of attention due to its selective and specific sensitivity towards biomolecules and cations, it behaves as a frontline contender for recognition moieties and their eventual applications as fluorogenic sensing agents have received increasing interest. The binding properties of calix[4]pyrrole can be modulated by diverse structural modifications or by the change of solvent. Accessibility, high fluorescence quantum yield, and biological activity of aminoanthraquinone and aminoquinoline has attracted as a fluorophore, polymer additives and medicinal agents. Due to the tunable properties of aminoanthraquinone and aminoquinoline and calix[4]pyrrole scaffold fixing up may lead to development of new sensor. In this regards we have synthesised two derivatives of calix[4]pyrrole bearing carboxylic group i.e. ABCPTAA & ABCPTAQ which binds selectively with OTC and Hg(II) ions, respectively. The experimental data are very well supported by spectroscopic as well as computational studies.

【 授权许可】

Unknown