Single Dose Benzathine Penicillin G in the Treatment of Acute Tonsillopharyngitis Due to Group A Beta-Hemolytic Streptococci

Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi

卷:7

Birsen MUTLU¹  Haluk VAHABOĞLU¹  Zeynep AKÇAM²  Hakan LEBLEBİCİOĞLU²  Mustafa AKÇAM³ 

[1] Kocaeli Üniversitesi Tıp Fakültesi, Klinik Bakteriyoloji ve İnfeksiyon Hastalıkları Anabilim Dalı, KOCAELİ;

[2] Ondokuz Mayıs Üniversitesi Tıp Fakültesi, Klinik Bakteriyoloji ve İnfeksiyon Hastalıkları Anabilim Dalı,;

[3] Sağlık Bakanlığı Çocuk Hastalıkları ve Doğumevi, SAMSUN;

关键词: Group A beta-hemolytic streptococci;    Tonsillopharyngitis;   

DOI  :  

来源: DOAJ

【 摘 要 】

The success rate of single dose benzathine penicillin G intramuscular (IM) injection in the treatment of tonsillopharyngitis caused by group A beta-hemolytic streptococci (GABHS) was investigated. Totally 179 patients in the acute phase of tonsillopharyngeal infection with physical findings of; tonsillar redness, edema, grayish white exudate, enlarged lymph nodes were enrolled into this prospective study. Throat cultures and rapid immunoassay test for the qualitative detection of group A streptococcus antigen was used for all patients. Throat cultures were found positive in 74 (41.4%) patients, whereas rapid immunoassay test was found positive in 69 (38.5%) patients. Single injection dose of benzathine penicillin G was administered to the patients with positive antigen test. Patients were checked with throat samples at 3 and 17 days after injection. The failure rate of this treatment was found as 5% at the end of 17 days.

【 授权许可】

Unknown