Axial length and cone density as assessed with adaptive optics in myopia

Indian Journal of Ophthalmology

卷:63

关键词: Community;    digital imaging;    Karnataka Internet-assisted Diagnosis of Retinopathy of Prematurity;    retinopathy of prematurity;    telemedicine;    universal screening;    Age-related macular degeneration;    en-face optical coherence tomography;    polypoidal choroidal vasculopathy;    Choroid;    enhanced depth imaging technique;    swept source optical coherence tomography;    Choroidal imaging;    choroidal thickness;    retinal dystrophies;    Choroidal neovascularization;    idiopathic juxtafoveal telangiectasis;    juxtafoveal retinal telangiectasia;    lutein;    macular edema;    macular pigment;    macular telangiectasia;    Müller cells;    parafoveal telangiectasis;    perifoveal telangiectasis;    retinal angiomatous proliferation;    retinal telangiectasis;    subretinal neovascularization;    zeaxanthin;    Microscope-integrated optical coherence tomography;    RESCAN;    spectral domain optical coherence tomography;    vitreoretinal surgery;    Central reading center;    randomized controlled trial;    standard operating procedure;    Fundus autofluorescence;    lipofuscin;    retina;    retinal imaging;    Cystoid macular edema;    dexamethasone implant;    external limiting membrane;    optical coherence tomography;    Ozurdex;    serous retinal detachment;    uveitis;    Adaptive optics;    axial length;    cone density;    myopia;   

DOI  :  10.4103/0301-4738.159876

来源: DOAJ

【 摘 要 】

Aim: To assess the variations in cone mosaic in myopia and its correlation with axial length (AL). Subjects and Methods: Twenty-five healthy myopic volunteers underwent assessment of photoreceptors using adaptive optics retinal camera at 2° and 3° from the foveal center in four quadrants superior, inferior, temporal and nasal. Data was analyzed using SPSS version 17 (IBM). Multivariable regression analysis was conducted to study the relation between cone density and AL, quadrant around the fovea and eccentricity from the fovea. Results: The mean cone density was significantly lower as the eccentricity increased from 2° from the fovea to 3° (18,560 ± 5455-16,404 ± 4494/mm 2 respectively). There was also a statistically significant difference between four quadrants around the fovea. The correlation of cone density and spacing with AL showed that there was a significant inverse relation of AL with the cone density. Conclusion: In myopic patients with good visual acuity cone density around the fovea depends on the quadrant, distance from the fovea as well as the AL. The strength of the relation of AL with cone density depends on the quadrant and distance.

【 授权许可】

Unknown