Discrepancy between Lung Function Measurements at Home and in the Hospital in Children with Asthma and CF

Journal of Clinical Medicine

卷:9

Bjorn Winkens¹  MichielA.G.E. Bannier²  Quirijn Jöbsis²  Edward Dompeling²  FrederickL.G.R. Gerzon² 

[1] Department of Methodology and Statistics, CAPHRI, MUMC+, 6229 HA Maastricht, The Netherlands;

[2] Department of Paediatric Pulmonology, School for Public Health and Primary Care (CAPHRI), Maastricht University Medical Centre (MUMC+), 6202 AZ Maastricht, The Netherlands;

关键词: home monitoring;    lung function;    asthma;    cystic fibrosis;    children;    telemedicine;   

DOI  :  10.3390/jcm9061617

来源: DOAJ

【 摘 要 】

The Coronavirus pandemic stresses the importance of eHealth techniques to monitor patients at home. Home monitoring of lung function in asthma and cystic fibrosis (CF) may help to detect deterioration of lung function at an early stage, but the reliability is unclear. We investigated whether lung function measurements at home were comparable to measurements during clinical visits. We analysed prospectively collected data of two one-year observational cohort studies in 117 children (36 with CF and 81 with asthma). All patients performed forced expiratory volume in one second (FEV₁) measurements with a monitor at home. Paired FEV₁ measurements were included if the measurement on the home monitor was performed on the same day as the FEV₁ measurement on the pneumotachometer during a two monthly clinical visit. Bland-Altman plots and linear mixed model analysis were used. The mean difference (home measurement was subtracted from clinical measurement) in FEV₁ was 0.18 L in CF (95% confidence interval (CI) 0.08–0.27 L; p < 0.001) and 0.12 L in asthma (95%CI 0.05–0.19 L; p < 0.001). FEV₁ measurements at home were significantly lower than clinically obtained FEV₁ measurements, which has implications for the application of this technique in the daily clinical situation.

【 授权许可】

Unknown