Epithelial-myoepithelial carcinoma on lower lip and microinvasive verrucous carcinoma in vocal cord: Case report

İstanbul Kuzey Klinikleri

卷:7

Burak Karabulut¹  Murat Hakan Karabulut²  Merve Aydemir²  Itır Ebru Zemheri²  Begüm Çalım Gürbüz²  Hande Nur Inceman² 

[1] Department of Otolaryngology, Istanbul Health Sciences University, Umraniye Training and Research Hospital, Istanbul, Turkey;

[2] Department of Pathology, Health Sciences University, Umraniye Training and Research Hospital, Istanbul, Turkey;

关键词: epithelial myoepithelial carcinoma;    microinvasive;    minor salivary glands;    verrucous carcinoma.;   

DOI  :  10.14744/nci.2019.48991

来源: DOAJ

【 摘 要 】

Epithelial-myoepithelial carcinoma is a biphasic low-grade malignant tumor, which represents approximately 1% of all salivary gland tumors. This tumor occurs mostly in the parotid gland, followed by submandibular gland and minor salivary glands. Women, mostly fifth to the eighth decade of life, are commonly affected. Histopathologically, epithelial-myoepithelial carcinoma is composed of an inner single layer of eosinophilic cuboidal ductal cells and outer single or multiple layers of clear myoepithelial cells. We present a case of a 69 years old man who had a scar on lower the lip for 10 years and voice annoyance for three months. The biopsy for lower lip was reported 'infiltrative clear cell epithelioid neoplasm' and vocal cord biopsy result was 'verrucous carcinoma'. After cordectomy and wedge resection of the lower lip, histopathology revealed Epithelial-Myoepithelial Carcinoma for the lower lip and microinvasive verrucous carcinoma for the left vocal cord. Our case has a very uncommon location and presentation for EMC. The tumor location was minor salivary glands of the lower lip and the clinical presentation was quite different. Coexistence with microinvasive verrucous carcinoma of the vocal cord is the other unique part of our case.

【 授权许可】

Unknown