期刊论文详细信息
Horizonte Médico 卷:17
Depletion of blood supply and cost due to indeterminate donations at the Guillermo Almenara Irigoyen National Hospital
Jeel Moya-Salazar1  Rommel Díaz R2  Liz Pio-Dávila3 
[1] M.Sc(C). M.T., Departamento de Ciencias Celulares y Moleculares, Facultad de Ciencias y Filosofía. Universidad Peruana Cayetano Heredia Lima, Perú,Hospital Nacional Docente Madre Niño San Bartolomé. Lima, Perú ;
[2] M.T. Especialista en control de calidad en bancos de sangre. EsSalud, Servicio de Banco de Sangre y Medicina Transfusional, Hospital Nacional Guillermo Almenara Irigoyen. Lima, Perú;
[3] MLT. BSc., Hospital Nacional Dos de Mayo. Lima, Perú;
关键词: Gray zone;    blood donation;    infectious markers;    screening;   
DOI  :  
来源: DOAJ
【 摘 要 】

Objective: To evaluate the depletion of blood supply and the cost due to indeterminate donations at Hospital NacionalGuillermo Almenara Irigoyen during 2014.Materials and methods: A retrospective cross-sectional study and a cost-utility analysis were conducted in donationsshowing results in the gray zone (sample value/cutoff value between >0.85 and <1) after a serological screening of seveninfectious markers (HIV, HBsAg, HBcAb, HCV, HTLV-1/2, syphilis and Chagas disease) and the simultaneous determinationof the HIV Ag/Ab combo by means of a fourth generation ELISA. Data was encoded and tabulated using the e-Delphyn®system. The cost-utility analysis was performed considering the current exchange rate.Results: Out of 9,560 donations, 20.7% (1977 donations) showed results in the gray zone which caused a loss of 863.9liters of blood and USD 92,640. The highest and lowest rate of seroprevalence were observed in HBcAb with 10.18% (973indeterminate test results) and anti-HIV with 0.39% (47 indeterminate test results), respectively (p<0.05). No significantdifferences were found between the anti-HIV y HIV Ag/Ab combo screening methods (p=0.776).Conclusions: It was demonstrated that more than 800 liters of discarded blood generated a more than USD 90,000cost due to indeterminate donations causing economic damages to the hospital budget and a depletion of blood supplyavailable for patients at Hospital Nacional Guillermo Almenara Irigoyen.

【 授权许可】

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