The inverse association between unhealthy eating habit and mucosal healing among patients with ulcerative colitis

BMC Gastroenterology

卷:21

Kana Shiraishi¹  Masakazu Hanayama¹  Yoichi Hiasa¹  Yu Hashimoto¹  Kazuhiro Tange¹  Shogo Kitahata¹  Tomoyuki Ninomiya²  Kenichiro Mori²  Naozumi Shibata³  Aki Hasebe⁴  Seiyuu Suzuki⁵  Hideomi Tomida⁶  Eiji Takeshita⁶  Hidehiro Murakami⁷  Sen Yagi⁷  Yoshio Ikeda⁸  Yasunori Yamamoto⁸  Shinya Furukawa⁹  Katsuhisa Ohashi¹⁰ 

[1] Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine;

[2] Department of Gastroenterology, Ehime Prefectural Central Hospital;

[3] Department of Gastroenterology, Ehime Prefectural Niihama Hospital;

[4] Department of Gastroenterology, Shikoku Cancer Center;

[5] Department of Gastroenterology, Sumitomo Besshi Hospital;

[6] Department of Inflammatory Bowel Diseases and Therapeutics, Ehime University Graduate School of Medicine;

[7] Department of Internal Medicine, Saiseikai Matsuyama Hospital;

[8] Endoscopy Center, Ehime University Hospital;

[9] Health Services Center, Ehime University;

[10] Ohashi Clinic Participating in Gastro-Enterology and Ano-Proctology;

关键词: Eating quickly;    Eating until full;    Skipping breakfast;    Eating habits;    Ulcerative colitis;   

DOI  :  10.1186/s12876-021-01724-6

来源: DOAJ

【 摘 要 】

Abstract Background Although the association between eating habits which can be modified and digestive diseases has been reported, to date, no research has evaluated the association between eating habits and ulcerative colitis (UC). Thus, we investigate the association between eating behavior and clinical outcome in Japanese patients with UC. Methods Eating quickly, eating until full, and skipping breakfast data was obtained from a self-administered questionnaire. Information on clinical outcome was collected from medical records. Mucosal healing (MH) and partial MH was defined as a Mayo endoscopic subscore of 0 or 0–1, respectively. Age, sex, BMI, current smoking, current drinking, prednisolone use, and anti-TNFα monoclonal antibody use were selected a priori as potential confounding factors. Results Study subjects consisted of 294 Japanese patients with UC. Eating at speed moderate and eating quickly were independently inversely associated with MH: the adjusted odds ratios (ORs) were 0.38 (95% confidence interval [CI] 0.16–0.85) and 0.38 (95% CI 0.17–0.81) (p for trend = 0.033). Eating until full was independently inversely associated with MH: the adjusted OR was 0.38 (95% CI 0.27–0.86). MH in patients who skipped breakfast was marginally lower than that in patients who did not skip breakfast. No association between eating habits and clinical remission or partial MH was found. Conclusion Among patients with UC, eating rate and eating until full may be independently inversely associated with MH but not clinical remission.

【 授权许可】

Unknown