Infectious Bronchitis Virus Variants: Molecular Analysis and Pathogenicity Investigation

International Journal of Molecular Sciences

卷:18

Shu-Yi Lin¹  Hui-Wen Chen¹ 

[1] Department of Veterinary Medicine, National Taiwan University, Taipei 10617, Taiwan;

关键词: infectious bronchitis virus;    variants;    genotypes;    antigenicity;    pathogenicity;   

DOI  :  10.3390/ijms18102030

来源: DOAJ

【 摘 要 】

Infectious bronchitis virus (IBV) variants constantly emerge and pose economic threats to poultry farms worldwide. Numerous studies on the molecular and pathogenic characterization of IBV variants have been performed between 2007 and 2017, which we have reviewed herein. We noted that viral genetic mutations and recombination events commonly gave rise to distinct IBV genotypes, serotypes and pathotypes. In addition to characterizing the S1 genes, full viral genomic sequencing, comprehensive antigenicity, and pathogenicity studies on emerging variants have advanced our understanding of IBV infections, which is valuable for developing countermeasures against IBV field outbreaks. This review of IBV variants provides practical value for understanding their phylogenetic relationships and epidemiology from both regional and worldwide viewpoints.

【 授权许可】

Unknown