New clustering module in BDPC bisulfite sequencing data presentation and compilation web application for DNA methylation analyses

BioTechniques

卷:47

Yingying Zhang¹  Christian Rohde¹  Albert Jeltsch¹  Heinrich Stamerjohanns¹  Kurt Hecher²  Richard Reinhardt³ 

[1] 1School of Engineering and Science, Jacobs University Bremen, Bremen, Germany;

[2] 2Department of Obstetrics and Fetal Medicine, Universitaetsklinikum Hamburg-Eppendorf (UKE), Hamburg, Germany;

[3] 3Max Planck Institute for Molecular Genetics, Berlin-Dahlem, Germany;

关键词: DNA methylation;    epigenetics;    bisulfite analysis;    methylome;    epigenome;    BiQ Analyzer;   

DOI  :  10.2144/000113196

来源: DOAJ

【 摘 要 】

The Bisulfite Sequencing Data Presentation and Compilation (BDPC) web interface for compilation and presentation of data from bisulfite sequencing DNA methylation studies has been improved by adding a new module. This module allows visualization of the whole data set in form of a heatmap of DNA methylation levels and clustering and comparison of tissue methylation patterns. It can also be used for data not processed by BDPC. In addition, several functions of the existing BDPC compilation module have been improved.

【 授权许可】

Unknown