The role of interleukin genes in the course of depression

Open Medicine

卷:11

Talarowska Monika¹  Gałecki Piotr¹  Szemraj Janusz² 

[1] Department of Adult Psychiatry, Medical University of Lodz, Lodz, Poland;

[2] Department of Medical Biochemistry, Medical University of Lodz, Lodz, Poland;

关键词: first episode;    recurrent depressive disorder;    il-1;    il-6;    il-10;   

DOI  :  10.1515/med-2016-0009

来源: DOAJ

【 摘 要 】

Research studies conducted in recent years have confirmed that in the absence of medical illnesses, depressive disorders are associated with upregulation of many inflammatory cytokines such as tumor necrosis factor-aplha (TNF-α), interleukin-1 and 6 (IL-1,IL-6). The main objective of the study was to examine whether recurrent depressive disorders (rDD) are accompanied by more profound inflammatory disturbances than the first episode of depression (ED-I). The analysis included the expression of mRNA and protein levels of three interleukins namely. IL-1, IL-6 and IL-10.

【 授权许可】

Unknown