Recent advances in understanding and managing asthma [version 1; referees: 2 approved]

F1000Research

卷:5

Su-Ling Loo¹  Peter A.B. Wark¹ 

[1] Priority Research Centre for Healthy Lungs, University of Newcastle, Hunter Medical Research Institute, New Lambton, NSW, 2305, Australia;

关键词: Allergy & Hypersensitivity;    Asthma & Allergic Rhinitis;    Immunity to Infections;    Immunopharmacology & Hematologic Pharmacology;    Innate Immunity;    Integrative Physiology;    Leukocyte Signaling & Gene Expression;    Medical Microbiology;    Respiratory Pediatrics;    Respiratory Pharmacology;    Virology;   

DOI  :  10.12688/f1000research.9236.1

来源: DOAJ

【 摘 要 】

This review highlights the important articles published in the area of asthma research from January 2015 to July 2016. In basic science, significant advances have been made in understanding the link between the innate immune response and type II acquired immune responses in asthma and the role of the airway epithelium. Novel information continues to emerge with regard to the pathogenesis and heterogeneity of severe asthma. There have been important translational clinical trials in the areas of childhood asthma, treatment of allergy to improve asthma outcomes, and improving drug delivery to optimize the management of asthma. In addition, there are increasing data concerning the application of biological agents to the management of severe asthma. This body of work discusses the most notable advances in the understanding and management of asthma.

【 授权许可】

Unknown