期刊论文详细信息
BMC Research Notes 卷:11
Modes of mechanical ventilation vary between hospitals and intensive care units within a university healthcare system: a retrospective observational study
Craig S. Jabaley1  Milad Sharifpour1  Jayashree K. Raikhelkar1  James M. Blum1  Robert F. Groff1 
[1] Division of Critical Care Medicine, Department of Anesthesiology, Emory University;
关键词: Positive pressure ventilation;    Respiratory failure;    Mechanical ventilators;    Noninvasive ventilation;    Ventilator weaning;    Intensive care;   
DOI  :  10.1186/s13104-018-3534-z
来源: DOAJ
【 摘 要 】

Abstract Objective As evidence-based guidance to aid clinicians with mechanical ventilation mode selection is scant, we sought to characterize the epidemiology thereof within a university healthcare system and hypothesized that nonconforming approaches could be readily identified. We conducted an exploratory retrospective observational database study of routinely recorded mechanical ventilation parameters between January 1, 2010 and December 31, 2016 from 12 intensive care units. Mode epoch count proportions were examined using Chi squared and Fisher exact tests as appropriate on an inter-unit basis with outlier detection for two test cases via post hoc pairwise analyses of a binomial regression model. Results Final analysis included 559,734 mode epoch values. Significant heterogeneity was demonstrated between individual units (P < 0.05 for all comparisons). One unit demonstrated heightened utilization of high-frequency oscillatory ventilation, and three units demonstrated frequent synchronized intermittent mandatory ventilation utilization. Assist control ventilation was the most commonly recorded mode (51%), followed by adaptive support ventilation (23.1%). Volume-controlled modes were about twice as common as pressure-controlled modes (64.4% versus 35.6%). Our methodology provides a means by which to characterize the epidemiology of mechanical ventilation approaches and identify nonconforming practices. The observed variability warrants further clinical study about contributors and the impact on relevant outcomes.

【 授权许可】

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