Limonin isolated from the seeds of Citrus limetta (Indian sweet lemon)

IUCrData

卷:1

Quynh Nguyen Do Nhu¹  A. K. Bauri²  Sabine Foro³ 

[1] Accident and Emergency Department, Franco Vietnamese Hospital, 7 Nguyen Luong Bang Street, Ho Chi Minh City, Vietnam;

[2] Bioorganic Division, Bhabha Atomic Research Centre, Trombay, Mumbai 400 085, India;

[3] FB Material-und Geowissenschaften, Technische Universität Darmstadt, Alarich-Weiss-Strasse 2, 64287 Darmstadt, Germany;

关键词: crystal structure;    limonin;    tetracyclic terpenoid;    polyoxgenated;    antiproliferative;    C—H...O hydrogen bonding;   

DOI  :  10.1107/S2414314616001723

来源: DOAJ

【 摘 要 】

The title molecule, C26H30O8 [systematic name: (4aS,14bR)-12-(furan-3-yl)-6,6,8a,12a-tetramethyldecahydro-1H,3H-oxireno[2,3-d]pyrano[4′,3′:3,3a]isobenzofuro[5,4-f]isochromene-3,8,10(6H,9aH)-trione], commonly known as limonin, is an antiproliferative polyoxgenated bioactive molecule. It comprises a fused cyclic system containing a cyclohexane (D), a cyclohexanone (C), a furan (B), an epoxide and two lactone rings (A and E). In addition to these rings, a second furan ring (F) is present as a substituent. Only the cyclohexane (D) ring has a chair conformation; the other six-membered rings (A, C and E) have twist-boat conformations due to steric hinderance or bonding strain. In the crystal, molecules are linked by C—H...O hydrogen bonds, forming a three-dimensional structure.

【 授权许可】

Unknown