Metabolic Outcomes in Southern Italian Preadolescents Residing Near an Industrial Complex: The Role of Residential Location and Socioeconomic Status

International Journal of Environmental Research and Public Health

卷:16

RobertO. Wright¹  Luz Claudio¹  Manuela Oppini²  Giuseppa Cagna²  Silvia Zoni²  Miriana Montemurro²  Chiara Fedrighi²  Donatella Placidi²  Esha Bansal²  Stefano Guazzetti²  RobertoG. Lucchini²  Shaye Carver²  Donald Smith³  Stefano Renzetti⁴  Michele Conversano⁵  Augusto Giorgino⁵ 

[1] Department of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA;

[2] Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, 25123 Brescia, Italy;

[3] Department of Microbiology and Environmental Toxicology, University of California Santa Cruz, Santa Cruz, CA 95064, USA;

[4] Department of Molecular and Translational Medicine, University of Brescia, 25123 Brescia, Italy;

[5] Department of Prevention, Local Health Authority of Taranto, 74121 Taranto, Italy;

关键词: children;    socioeconomic status;    residential location;    industrial;    air pollution;    body mass index;    BMI;    blood glucose;    obesity;   

DOI  :  10.3390/ijerph16112036

来源: DOAJ

【 摘 要 】

Evidence suggests that environmental exposures and socioeconomic factors may interact to produce metabolic changes in children. We assessed the influence of residential location and socioeconomic status (SES) on pediatric body mass index (BMI) Z-score and fasting blood glucose (FBG) concentration. Participants included 214 children aged 6−11 years who live near a large industrial complex in Taranto, Italy. Participants were grouped into residential zones based on the distance between their home address and the complex periphery (Zone 1: 0.000−4.999 km, Zone 2: 5.000−9.999 km, Zone 3: 10.000−15.000 km). BMI Z-scores were calculated via World Health Organization (WHO) pediatric reference curves. FBG was obtained via venous blood sampling. Closer residential location to the industrial complex on the order of 5.000 km was significantly associated with worsened metabolic outcomes, particularly in female children. Zone 1 participants had higher BMI-adjusted FBG than Zone 2 and 3 participants (p < 0.05 versus Zone 2; p < 0.01 versus Zone 3). SES did not significantly influence BMI-adjusted FBG. Moreover, BMI Z-scores indicated high rates of overweight (22.0%) and obesity (22.9%) in the cohort. BMI Z-score was not significantly associated with SES or residential zone but was negatively associated with maternal education level (p < 0.05). These results offer new evidence that residing near industrial activity may predict adverse effects on child metabolic health.

【 授权许可】

Unknown