Optimal Management of Patients with Severe Coronary Artery Disease following Multidisciplinary Heart Team Approach—Insights from Tertiary Cardiovascular Care Center

International Journal of Environmental Research and Public Health

卷:19

Radosław Wilimski¹  Paweł Czub¹  Szymon Jonik²  Radosław Piątkowski²  Marcin Grabowski²  Zenon Huczek²  Janusz Kochman²  Tomasz Mazurek²  Ewa Pędzich-Placha²  Monika Budnik²  Arkadiusz Pietrasik²  Piotr Scisło²  Jakub Maksym²  Grzegorz Opolski²  Michał Marchel²  Adam Rdzanek² 

[1] Department of Cardiac Surgery, Medical University of Warsaw, Banacha 1a Str., 01-267 Warsaw, Poland;

[2] Department of Cardiology, Medical University of Warsaw, Banacha 1a Str., 01-267 Warsaw, Poland;

关键词: multidisciplinary heart team;    multivessel coronary artery disease;    coronary artery bypass grafting;    percutaneous coronary intervention;    optimal medical therapy;   

DOI  :  10.3390/ijerph19073933

来源: DOAJ

【 摘 要 】

Background: The purpose of this retrospective study was to investigate outcomes of patients with severe coronary artery disease (CAD) after implementing various treatment strategies following multidisciplinary Heart Team (MHT) discussion. Methods Primary and secondary endpoints and quality of life during a mean (SD) follow-up of 37 (14) months of patients with severe CAD (three-vessel [3-VD] or/and left main [LM] disease) qualified after MHT discussion to optimal medical treatment (OMT) alone, OMT and coronary artery bypass grafting (CABG), or OMT and percutaneous coronary intervention (PCI) were evaluated. As the primary endpoint, major adverse cardiac or cerebrovascular events (MACCE) (i.e., death from any cause, stroke, myocardial infarction, or repeat/need for revascularization) were considered. Result: From 2016 to 2019, 176 MHT meetings were held, and a total of 1286 participants with severe CAD and completely implemented MHT decisions (OMT, CABG, or PCI for 251, 356, and 679 patients, respectively) were included. The occurrence of the primary endpoint was significantly increased in OMT-group (154 (61.4%) vs. CABG and PCI groups—110 (30.9%) and 302 (44.5%) patients, respectively (p < 0.05). For interventional strategies only—CABG was associated with reduced rates of MACCE and repeat revascularization, while the superiority of PCI for stroke and disabling stroke was observed (p < 0.05). The general health status assessed at the end of the follow-up was significantly better for patients who underwent CABG or PCI than in the OMT group (p < 0.05). Conclusions: In this real-life study, we presented a single-center experience of providing optimal medical care for patients with severe CAD following MHT discussion.

【 授权许可】

Unknown