COVID-19 vaccination intention and vaccine characteristics influencing vaccination acceptance: a global survey of 17 countries

Infectious Diseases of Poverty

卷:10

Jamil Ahmed¹  Abhishek Lachyan¹  Mahmoud Danaee¹  Haridah Alias¹  Di Khanh Nguyen²  Zhijian Hu³  Li Ping Wong³  Carla Zi Cai³  Yulan Lin³  Muditha Atapattu⁴  Gregory D. Zimet⁵  Guoxi Cai⁶  Yixiao Lu⁶  Farhana Nishat Seheli⁷  Tasmi Quazi-Bodhanya⁸  Si Ying Tan⁹  Fatma Alhammadi¹⁰  Samira Mohajer¹¹  Qinjian Zhao¹²  Milkar D. Madhale¹³ 

[1] Centre for Epidemiology and Evidence-Based Practice, Department of Social and Preventive Medicine, Faculty of Medicine, University of Malaya;

[2] Department of Academic Affairs and Testing, Dong Nai Technology University;

[3] Department of Epidemiology and Health Statistics, Fujian Provincial Key Laboratory of Environment Factors and Cancer, School of Public Health, Fujian Medical University;

[4] Department of Nursing, Faculty of Allied Health Sciences, University of Peradeniya;

[5] Department of Pediatrics, School of Medicine, Indiana University;

[6] Department of Public Health, Nagasaki University Graduate School of Biomedical Sciences;

[7] Institute of Epidemiology, Disease Control & Research (IEDCR);

[8] Leadership Dialogue;

[9] Leadership Institute for Global Health Transformation, Saw Swee Hock School of Public Health, National University of Singapore;

[10] Ministry of Health and Prevention (MOHAP);

[11] Nursing and Midwifery Care Research Center, Mashhad University of Medical Sciences;

[12] State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Institute of Diagnostics and Vaccine Development in Infectious Diseases, School of Public Health, Xiamen University;

[13] Vijaya College of Nursing, Belgaum;

关键词: COVID-19 vaccine;    Vaccination intention;    Vaccine characteristics;    Vaccination acceptance;    Vaccine choice;   

DOI  :  10.1186/s40249-021-00900-w

来源: DOAJ

【 摘 要 】

Abstract Background The availability of various types of COVID-19 vaccines and diverse characteristics of the vaccines present a dilemma in vaccination choices, which may result in individuals refusing a particular COVID-19 vaccine offered, hence presenting a threat to immunisation coverage and reaching herd immunity. The study aimed to assess global COVID-19 vaccination intention, vaccine characteristics influencing vaccination acceptance and desirable vaccine characteristics influencing the choice of vaccines. Methods An anonymous cross-sectional survey was conducted between 4 January and 5 March 2021 in 17 countries worldwide. Proportions and the corresponding 95% confidence intervals (CI) of COVID-19 vaccine acceptance and vaccine characteristics influencing vaccination acceptance were generated and compared across countries and regions. Multivariable logistic regression analysis was used to determine the factors associated with COVID-19 vaccine hesitancy. Results Of the 19,714 responses received, 90.4% (95% CI 81.8–95.3) reported likely or extremely likely to receive COVID-19 vaccine. A high proportion of likely or extremely likely to receive the COVID-19 vaccine was reported in Australia (96.4%), China (95.3%) and Norway (95.3%), while a high proportion reported being unlikely or extremely unlikely to receive the vaccine in Japan (34.6%), the U.S. (29.4%) and Iran (27.9%). Males, those with a lower educational level and those of older age expressed a higher level of COVID-19 vaccine hesitancy. Less than two-thirds (59.7%; 95% CI 58.4–61.0) reported only being willing to accept a vaccine with an effectiveness of more than 90%, and 74.5% (95% CI 73.4–75.5) said they would accept a COVID-19 vaccine with minor adverse reactions. A total of 21.0% (95% CI 20.0–22.0) reported not accepting an mRNA vaccine and 51.8% (95% CI 50.3–53.1) reported that they would only accept a COVID-19 vaccine from a specific country‐of‐origin. Countries from the Southeast Asia region reported the highest proportion of not accepting mRNA technology. The highest proportion from Europe and the Americas would only accept a vaccine produced by certain countries. The foremost important vaccine characteristic influencing vaccine choice is adverse reactions (40.6%; 95% CI 39.3–41.9) of a vaccine and effectiveness threshold (35.1%; 95% CI 33.9–36.4). Conclusions The inter-regional and individual country disparities in COVID-19 vaccine hesitancy highlight the importance of designing an efficient plan for the delivery of interventions dynamically tailored to the local population. Graphic Abstract

【 授权许可】

Unknown